发明名称 Oral microemulsion composition comprising biphenyldimethyldicarboxylate and silybin
摘要 A microemulsion composition comprising biphenyldimethyldicarboxylate (BDD) and silybin or a derivative thereof, or a <i>Carduus marianus</i> extract containing silybin and derivatives thereof, as active ingredients; a co-surfactant; a surfactant; and an oil provides a synergistic therapeutic effect for liver diseases due to the complementary work of the two kinds of active ingredients having different working mechanisms without any adverse side effect or an antagonism, and high <i>in vivo</i> bioavailabilities of both of the active ingredients, when orally administered.
申请公布号 US7485326(B2) 申请公布日期 2009.02.03
申请号 US20040576196 申请日期 2004.10.21
申请人 HANMI PHARM CO., LTD. 发明人 WOO JONG SOO;JUNG SI YOUNG;KIM AE GUK
分类号 A61K36/28;A61K9/107;A61K9/48;A61K31/19;A61K31/357;A61K31/765;A61K36/00;A61K45/06 主分类号 A61K36/28
代理机构 代理人
主权项
地址