发明名称 Anticancer compositions, and methods of making and using the same
摘要 Compositions, containing a ruthenium(III) complex and a heterocycle, methods for their manufacture, medicament containing these compositions and a kit. The invention relates to a composition (A), obtained by reacting a compound of the general formula (I) <?in-line-formulae description="In-line Formulae" end="lead"?>M3-n-p-2pr[RUX6-n-p-q-2rBn(H2O)p(OH)q(O)r]2r+1 (I)<?in-line-formulae description="In-line Formulae" end="tail"?> with a compound of the general formula (II) <?in-line-formulae description="In-line Formulae" end="lead"?>B'(HX')s (II).<?in-line-formulae description="In-line Formulae" end="tail"?> Furthermore, the invention relates to a composition (B), obtained by mixing a compound of the general formula (III) <?in-line-formulae description="In-line Formulae" end="lead"?>(B'H)3-n-p-2pr[RUX6-n-p-q-2rBn(H2O)p(OH)q(O)r]2r+1 (III)<?in-line-formulae description="In-line Formulae" end="tail"?> with a compound of the general formula (IV) <?in-line-formulae description="In-line Formulae" end="lead"?>MX' (IV).<?in-line-formulae description="In-line Formulae" end="tail"?>
申请公布号 US7485659(B2) 申请公布日期 2009.02.03
申请号 US20070696116 申请日期 2007.04.03
申请人 发明人
分类号 A61K31/415;C07D231/56 主分类号 A61K31/415
代理机构 代理人
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