NEW COMPOUNDS OF 5-HT7 RECEPTOR ANTAGONIST

摘要

A novel compound having antagonism in 5-HT7 receptor is provided to be usefully used for relax and treatment of disease mediated in 5-HT7 or symptom and to have good pharmaceutical properties. A novel compound having antagonism in 5-HT7 receptor is represented by a chemical formula (I). In the chemical formula (I), R1 is substitution radical selected from a group consisting of alkyl of C1~C4 substituted for halogen or nitro and alkoxy of C1~C4 or phenyl or benzyl; R2 is anisole naphthalene or quinoline; R3 is H, C1~C4 alkyl, halogen or C1~C4 alkoxy; R4 is H or C1~C3 alkyl not substituted for cyclo C5~C7 alkyl or phenyl.