| 发明名称 |
Stabilized single domain antibodies |
| 摘要 |
<p>Disclosed are polypeptide constructs comprising: -at least one single domain antibody directed against a therapeutic and/or diagnostic target, and -at least one single domain antibody directed against a serum protein; such that at least one of the single domain antibodies is devoid of light chains. Also disclosed are methods for stabilising single domain antibodies in biological circulatory systems.</p> |
| 申请公布号 |
NZ540195(A) |
申请公布日期 |
2009.01.31 |
| 申请号 |
NZ20030540195 |
申请日期 |
2003.11.07 |
| 申请人 |
ABLYNX N.V. |
发明人 |
SILENCE, KAREN;LAUWEREYS, MARC;DREIER, TORSTEN |
| 分类号 |
A61K39/395;A61P11/06;A61P19/02;A61P31/06;A61P31/16;A61P35/00;A61P37/06;C07K16/10;C07K16/12;C07K16/18;C07K16/24;C07K16/28;C07K16/30;C07K16/36;C07K16/40;C07K16/42;C07K16/46;C12N15/13;G01N33/577;(IPC1-7):C07K16/18 |
主分类号 |
A61K39/395 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
