Methods and compositions for the treatment of central nervous system disorders

摘要

Disclosed is a pharmaceutical composition for treatment or prophylaxis of a central nervous system disorder for administration to a subject suffering from the disorder, comprising a compound of formula I that stimulates a nicotine receptor; either or both of at least one inhibitor of the AT2 receptor or at least one inhibitor of a substance that stimulates the AT2 receptor, and a pharmaceutically acceptable carrier.