发明名称 Therapeutic agents comprising an anti-angiogenic agent, in particular a VEGF receptor tyrosine kinase inhibitor, in combination with an Src-inhibitor and their therapeutic use
摘要 The combination of a VEGF receptor tyrosine kinase inhibitor with an inhibitor of the Src family of non-receptor tyrosine kinases can be used to produce a medicament for the substantially normotensive treatment of disease states associated with angiogenesis selected from cancer, diabetes, psoriasis, rheumatoid arthritis, Kaposi's sarcoma, haemangioma, lymphoedema, acute and chronic nephropathies, atheroma, arterial restenosis, autoimmune diseases, acute inflammation, excessive scar formation and adhesions, endometriosis, dysfunctional uterine bleeding and ocular diseases with retinal vessel proliferation including age-related macular degeneration.
申请公布号 NZ542348(A) 申请公布日期 2009.01.31
申请号 NZ20040542348 申请日期 2004.05.04
申请人 ASTRAZENECA AB 发明人 CURWEN, JON OWEN;WEDGE, STEPHEN ROBERT
分类号 A61K45/06;A61P9/12;A61P35/00;(IPC1-7):A61K31/498;A61K31/517 主分类号 A61K45/06
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