发明名称 18-METHYL-19-NOR-ANDROST-4-EN-17,17-SPIROETHER (18-METHYL-19-NOR-20- SPIROX-4-EN-3-ONE) AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME.
摘要 <p>The invention relates to novel 18-methyl-19-nor-androst-4-en-17,17- spiroether of general formula (I), where Z = O, two H, =NOR or =NNHSO<sub>2</sub>R, R = H, or straight or branched chain C<sub>1-4</sub> or C<sub>3-4</sub>alkyl, R4 = H, halogen, or CF<sub>3</sub> and R6 and/or R7 are alpha- or ÿ-positioned and R6 and R7 independently = H or straight or branched chain C<sub>1-4</sub> or C<sub>3-4</sub>alkyl or a straight or branched chain C<sub>2-4</sub> or C<sub>3-4</sub>alkylene or a saturated C<sub>3-5</sub> cycloalkyl, or together form a methylene group or a double bond. The novel compounds have gestagenic and antimineralcorticoid action.</p>
申请公布号 MX2009000082(A) 申请公布日期 2009.01.23
申请号 MX20090000082 申请日期 2007.06.29
申请人 BAYER SCHERING PHARMA AKTIENGESELLSCHAFT 发明人 ROLF BOHLMANN;JAN HUEBNER;HANS-PETER MUHN;KATJA PRELLE;STEFFEN BORDEN;JOACHIM KUHNKE;NORBERT GALLUS;FREDERIK MENGES
分类号 C07J53/00;A61K31/58;A61P5/34;A61P5/42 主分类号 C07J53/00
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