| 发明名称 |
MACROCYCLIC INDOLE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C INFECTIONS |
| 摘要 |
<p>A class of macrocyclic compounds of formula (I), wherein R7,A,Ar, B,D, F, M, Q1, Q2, W, X, Y and Z are defined herein, that are useful as inhibitors of viral proteases, particularly the hepatitis C virus (HCV) NS3 protease, are provided. Alsoprovided are processes for the synthesis and use of such macrocyclic compounds for treating or preventing HCV infection.</p> |
| 申请公布号 |
WO2009010785(A1) |
申请公布日期 |
2009.01.22 |
| 申请号 |
WO2008GB50555 |
申请日期 |
2008.07.09 |
| 申请人 |
ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA;CONTE, IMMACOLATA;HABERMANN, JOERG;MACKAY, ANGELA CLAIRE;NARJES, FRANK;RICO FERREIRA, MARIA DEL ROSARIO;STANSFIELD, IAN |
发明人 |
CONTE, IMMACOLATA;HABERMANN, JOERG;MACKAY, ANGELA CLAIRE;NARJES, FRANK;RICO FERREIRA, MARIA DEL ROSARIO;STANSFIELD, IAN |
| 分类号 |
C07D513/16;A61K31/407;A61P31/12;C07D515/16 |
主分类号 |
C07D513/16 |
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