摘要 |
Methods and systems are provided for determining a condition of a selected region of epithelial tissue or an organ in a body as well as to diagnose disease, and to measure response to therapy, introduction of a drug and to assess the margins of a tumor or resection. The methods utilize through the tissue or organ electrical measurements with alternating current applied using one or more surface or internal electrodes and measuring the electrical response using one or more surface electrodes, preferably in combination with one or more electrodes in direct or indirect contact with epithelium comprising the organ under test. The methods are also useful in combination with DC measurements on the surface of the organ under test. Measurement of impedance, admittance, electropotential and dielectric properties is particularly useful, particularly as a function of frequency and position on and in the organ. |