发明名称 |
CONJUGATE PURIFICATION |
摘要 |
This application relates to methods for the purification of saccharide antigen-carrier protein conjugates. In particu-lar, the invention provides a method for purifying saccharide antigen-carrier protein conjugates from free carrier protein, such as CRM1 97, using hydroxyapatite. The invention further relates to methods of preparing vaccines, using this method. |
申请公布号 |
CA2693936(A1) |
申请公布日期 |
2009.01.22 |
申请号 |
CA20082693936 |
申请日期 |
2008.07.17 |
申请人 |
NOVARTIS AG |
发明人 |
BIGIO, MASSIMO;AVERANI, GIOVANNI;NORELLI, FRANCESCO;BERTI, FRANCESCO;BELLUCCI, CINZIA |
分类号 |
A61K47/48;A61K39/09;A61P31/04;B01D15/00;B01J20/04 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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