发明名称 |
6-PHENYL-1H-IMIDAZO[4,5-C]PYRIDINE-4-CARBONITRILE DERIVATIVES AS CATHEPSIN INHIBITORS |
摘要 |
The present invention relates to 6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives having the general Formula (I), to pharmaceutical compositions comprising the same as well as to the use of these derivatives for the preparation of a medicament for the treatment of cathepsin S related diseases such asatherosclerosis,obesity, inflammation and immune disorders, such as rheumatoid arthritis, psoriasis, cancer,and chronic pain, such as neuropathic pain.
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申请公布号 |
CA2693887(A1) |
申请公布日期 |
2009.01.22 |
申请号 |
CA20082693887 |
申请日期 |
2008.07.14 |
申请人 |
N.V. ORGANON |
发明人 |
CAI, JIAQIANG;RANKOVIC, ZORAN;JONES, PHILIP STEPHEN;BENNETT, DAVID JONATHAN;FRADERA, XAVIER |
分类号 |
C07D471/04;A61K31/437;A61P17/00;A61P19/00;A61P29/00 |
主分类号 |
C07D471/04 |
代理机构 |
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主权项 |
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地址 |
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