| 发明名称 |
TENOFOVIR DISOPROXIL HEMI-FUMARIC ACID CO-CRYSTAL |
| 摘要 |
<p>The present invention provides a novel crystalline form of Tenofovir disoproxil fumarate (Tenofovir DF), designated Co-crystal TDFA 2:1, methods for the preparation thereof and its use in pharmaceutical applications, in particular in anti-HIV medicaments. The crystalline form TDFA 2:1 can be used in combination with other anti-HIV medicaments such as Efavirenz, Emtricitabine, Ritonavir and/or TMC114.</p> |
| 申请公布号 |
WO2008143500(A4) |
申请公布日期 |
2009.01.22 |
| 申请号 |
WO2008NL00132 |
申请日期 |
2008.05.21 |
| 申请人 |
ULTIMORPHIX TECHNOLOGIES B.V.;DOVA, EVANTHIA;MAZUREK, JAROSLAW, MAREK;ANKER, JOHNNY |
发明人 |
DOVA, EVANTHIA;MAZUREK, JAROSLAW, MAREK;ANKER, JOHNNY |
| 分类号 |
C07F9/6561;A61K31/675;A61P31/18 |
主分类号 |
C07F9/6561 |
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