发明名称 Enhancement of Immune Response to Vaccine by Interferon Alpha
摘要 Exogenous cDNA capable of expressing interferon'' activity, exogenous interferon'' protein, inducers of endogenous interferon'' protein activity, inducers of endogenous interferon $ protein activity, inducers of endogenous interferon' activity, or inducers of other immune-enhancing activity can be combined with a vaccine to enhance an immune response. Specifically disclosed are adjuvant and vaccine combinations where the adjuvant comprises a cDNA capable of expressing interferon'' activity, a complex comprising polyriboinosinic-polyribocytidilic acid, or a complex comprising polyriboinosinic-polyribocytidilic acid, poly-L-lysine, and carboxymethylcellulose and where the vaccine is a live vaccine virus derived from a virus causing porcine reproductive and respiratory syndrome disease.
申请公布号 US2009022761(A1) 申请公布日期 2009.01.22
申请号 US20070928704 申请日期 2007.10.30
申请人 THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 发明人 ZUCKERMANN FEDERICO A.
分类号 A61K39/12;A61K39/39;C07H21/04 主分类号 A61K39/12
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