发明名称 PHARMACEUTICAL COMPOSITION CONTAINING COMPLEX OF PLATINUM AS ACTIVE SUBSTANCE, AND METHOD OF ITS OBTAINING
摘要 FIELD: medicine; pharmacology. ^ SUBSTANCE: composition contains complex of platinum as active substance, with, at least, one pharmaceutically comprehensible excipient, differing that it is formed from granulate with in the size of particles less than 0.5 mm, obtained by wet granulation of admixtures of a complex of the tetravalent platinum wetted by water, at least, one neutral saccharide and, at least, of one native and-or modified polysaccharide, unessentially, contains in capsule or bag or, unessentially, is pressed in the tablet form while the granulates surface, capsules or tablets, unessentially, is covered by layer, at least, one pharmaceutically comprehensible substance providing enteric dissolution of active substance only in intestine, and-or, at least, one pharmaceutically comprehensible substance. ^ EFFECT: controllable liberation of active substance. ^ 18 cl, 28 ex
申请公布号 RU2343913(C2) 申请公布日期 2009.01.20
申请号 RU20050133428 申请日期 2004.03.30
申请人 PLIVA-LAKHEMA A.S. 发明人 FRANTS ALESH;SOVA PETR
分类号 A61K31/282;A61K9/16;A61K9/20;A61K9/28;A61K9/48;A61K9/50;A61K47/26;A61K47/36;A61P35/00 主分类号 A61K31/282
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