发明名称 |
Troponin I polypeptide fragments and uses thereof |
摘要 |
Polypeptides corresponding to stable, circulating degradation products of troponin I (TnI) are described. The fragments comprise a sequence of the N-terminus of native cardiac TnI with 95-115 amino acid and additionally include fragments lacking about the 20-30 N-terminal amino acids. Utilities of these fragments and antibodies thereto include sensitive detection of myocardial infarction and purification of antibodies sensitive to the detection of troponin I degradation products.
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申请公布号 |
US7479278(B2) |
申请公布日期 |
2009.01.20 |
申请号 |
US20010941997 |
申请日期 |
2001.08.29 |
申请人 |
SPECTRAL DIAGNOSTICS, INC |
发明人 |
SHI QINWEI;LIU SHIGUI;LING MINGFU |
分类号 |
A61K39/00;A61K38/00;A61K39/12;A61K39/38;A61K45/00;A61K49/00;C07K14/47;C12N15/12 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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