发明名称 Hedgehog fusion proteins
摘要 A fusion polypeptide is described having the amino acid sequence X-Y-Z, or portion thereof, comprising the amino acid sequence of a hedgehog (X); Y is an optional linker moiety; and Z is a polypeptide comprising at least a portion of a polypeptide other than hedgehog. It is preferred that X is a human hedgehog. Mutants of hedgehog are also described.
申请公布号 US7479539(B1) 申请公布日期 2009.01.20
申请号 US20000129162 申请日期 2000.11.02
申请人 CURIS, INC. 发明人 STRAUCH KATHRYN;GARBER ELLEN A.;TAYLOR FREDERICK R.
分类号 C07K14/47;C12N15/09;A61K38/00;A61K38/17;A61K39/44;A61P25/14;A61P25/16;A61P25/28;A61P35/00;A61P43/00;C07K14/435;C07K14/46;C07K16/46;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/12;C12P21/02 主分类号 C07K14/47
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