发明名称 PIPERIDINYL SUBSTITUTED PYRROLIDINONES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1
摘要 ABSTRACT The present invention discloses novel compounds of Formula I: (I) having 11-Beta-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I, as well as methods of using the compounds and compositions to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, metabolic syndrome, and other conditions associated with 11-Beta-HSD type 1 activity. X-17433 PCT-1-
申请公布号 KR20090007371(A) 申请公布日期 2009.01.16
申请号 KR20087026195 申请日期 2007.04.27
申请人 ELI LILLY AND COMPANY 发明人 YORK JEREMY SCHULENBURG;WALLACE OWEN BRENDAN;XU YANPING
分类号 C07D401/04;A61K31/454;A61P3/00 主分类号 C07D401/04
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