摘要 |
MO-1 is a newly identified gene and gene product associated with morbid obesity. Isolated MO-1 nucleic acids, MO- 1 polypeptides, oligonucleotides that hybridize to MO-1 nucleic adds, and vectors, including expression vectors, comprising MO-1 nucleic acids are disclosed, as are isolated host cells, antibodies, transgenic non-human animals, compositions, and kits relating to MO-1. Methods of detecting the presence of MO-1 nucleic acid, screening for agents which affect MO-1 activity, and screening for MO-1 variants are also disclosed. |
申请人 |
MT. SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY;SHALATA, ADEL;MARTIGNETTI, JOHN;DESNICK, ROBERT |
发明人 |
SHALATA, ADEL;MARTIGNETTI, JOHN;DESNICK, ROBERT |