发明名称 MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS.
摘要 Compounds of the present invention and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator ("CFTR"). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.
申请公布号 MX2008012945(A) 申请公布日期 2009.01.15
申请号 MX20080012945 申请日期 2007.04.09
申请人 VERTEX PHARMACEUTICALS INCORPORATED. 发明人 BRIAN BEAR;PETER D.J. GROOTENHUIS;SARA S. HADIDA RUAH;FREDERICK VAN GOOR;JINGLAN ZHOU;MARK T. MILLER;JASON MCCARTNEY;MEHDI MICHEL JAMEL NUMA
分类号 C07D405/12;A61K31/404;A61P31/00;C07D405/14 主分类号 C07D405/12
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