发明名称 |
THERAPEUTIC COMPOUNDS FOR BLOCKING DNA SYNTHESIS OF POX VIRUSES |
摘要 |
<p>This invention provides methods of inhibiting replication of a poxvirus by contacting a poxvirus with a compound having formula I, formula XXI, formula XXXII, or formula XLI which in turn reduce, inhibit, or abrogate poxvirus DNA polymerase activity and/or its interaction with its processivity factor. Formula I, formula XXI, formula XXXII, or formula XLI can be utilized to treat humans and animals suffering from a poxvirus infection. Pharmaceutical compositions for treating poxvirus infected subjects are also provided.</p> |
申请公布号 |
WO2009008906(A2) |
申请公布日期 |
2009.01.15 |
申请号 |
WO2008US01553 |
申请日期 |
2008.02.06 |
申请人 |
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA;RICCIARDI, ROBERT, P.;YOUNG, JANICE, ELAINE P.;CIUSTEA, MIHAI |
发明人 |
RICCIARDI, ROBERT, P.;YOUNG, JANICE, ELAINE P.;CIUSTEA, MIHAI |
分类号 |
B62J1/28;B62J6/02;B62J25/00;B62K5/00;B62K21/16 |
主分类号 |
B62J1/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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