发明名称 NOVEL ANTIBODIES INHIBITING C-MET DIMERIZATION, AND USES THEREOF
摘要 <p>The present inventions relates to a process for the selection of anti c-Met antibodies capable to inhibit both ligand-dependant and ligand-independent activation of c-Met. More particularly, said process is based on the inhibition of the c-Met dimerization. In another aspect, the present invention concerns such antibodies and compositions comprising such antibodies for the preparation of a medicament to treat cancer. Diagnosis process and kits are also part of the invention.</p>
申请公布号 CA2888691(A1) 申请公布日期 2009.01.15
申请号 CA20082888691 申请日期 2008.07.10
申请人 PIERRE FABRE MEDICAMENT 发明人 GOETSCH, LILIANE
分类号 C12N15/13;A01K67/027;A61K39/395;A61K47/48;C07K14/71;C07K16/28;C07K16/46;C12N5/16;C12P21/08;G01N33/566 主分类号 C12N15/13
代理机构 代理人
主权项
地址