A COMPOUND SHOWING ANTI-INFLAMMATORY ACTIVITY AND ANTIVIRAL ACTIVITY, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, A PROCESS FOR OBTAINING THE SAME AND USE OF THE SAME IN THE TREATMENT OF EPIDEMIC KERATOCONJUNCTIVITES AND HERPETIC STROMAL KERATIS

摘要

The present invention refers to a compound having anti-inflammatory and antiviral activity according to the following structural formula (I): wherein, R1 and R3 are selected from H, HO-, R5-O-, HCOO-, R5- COO-, -OOC-R6-COO-, p-toluene sulphonate, phosphate, tartrate, maléate, sulphate, fluorine, chlorine, bromine, iodine and methanesulphonate, R2 is selected from H, HO-, R5-O-, HCOO-, R5-COO-, -OOC- R6-COO-, p-toluene sulphonate, phosphate, tartrate, maléate, sulphate, fluorine, chlorine, bromine and iodine, or -R1 and -R2 can be together -O-, ( CH3 ) 2- ( CO )2 - (6-- (CH3-CH2 )2-( CO)2- R4 and R5 are selected from H and linear or branched C1-C4 alkyl, R6 is -(CH2)n- wherein n equals to 1, 2 ó 3, and, formula (II) can be a single bond or double bond, to the pharmaceutical compositions comprising the same, to a process for preparing the same and to the use of the same for preparing pharmaceutical compositions. Particularly, the compounds of the invention are particularly useful for preparing ophthalmic pharmaceuticals for the treatment of diseases caused by adenovirus and preferably, epidemic keratocon junctivitis. Also, the compounds of the invention are particularly useful for preparing ophthalmic pharmaceuticals for the treatment of diseases caused by the herpes simplex type 1 (HSV-1) and preferably, herpetic stromal keratitis (HK).