| 摘要 |
<p>Oxidative cleavage involves oxidizing aryl vinyl compounds in presence of molecular oxygen to aldehydes or ketones, where an enzyme is used as a catalyst. The enzyme is selected from fungal peroxidases and laccases, halogen peroxidase, lignin peroxidase, horseradish peroxidase and cattle milk peroxidase. The oxidation is carried out in a bis-tris buffer, acetate buffer, formate buffer or phosphate buffer under oxygen pressure, preferably an organic solvent. The aryl vinyl compounds having general formula (I), and aldehyde having general formula (II), preferably vanillin, and ketone having general formula (III). n : 0-5; R 1>saturated or unsaturated hydrocarbon with 1-10C, which are replaced by heteroatoms and further substituted, amino, 1-6C alkylamino, 1-6C dialkylamino, halogens, hydroxy or cyano, where two of the substituents R 1> are joined to form a ring; and R 2> and R 3>independent of one another, H or one of the options for R 1>, where R 2> or R 3> are joined to an R 1> to form a ring. [Image] [Image] [Image].</p> |
