发明名称 INTRACELLULAR DELIVERY OF BIOLOGICAL EFFECTOR BY NEW TRANSPORTER PEPTIDE SEQUENCE
摘要 <p><P>PROBLEM TO BE SOLVED: To provide a transporter peptide movable across a biological membrane. <P>SOLUTION: The present invention provides a transporter peptide constituted of, at least one amino acid sequence selected from among a group consisting of (a) (X<SB>m</SB>RX<SB>o</SB>RX<SB>n</SB>); (b) (X<SB>m</SB>RRRX<SB>n</SB>); (c) (X<SB>m</SB>RRXRX<SB>n</SB>); and (d) (X<SB>m</SB>RXRRX<SB>n</SB>), wherein X is a non-basic amino acid; m is an integer of zero to fourteen; n is an integer, independent of m, between zero and fourteen; o is an integer, independent of m and n, between zero and five; and wherein the transporter peptide is movable across a biological membrane. The present invention also provides a method for screening a phage library to a specific transporter peptide. <P>COPYRIGHT: (C)2009,JPO&INPIT</p>
申请公布号 JP2009005694(A) 申请公布日期 2009.01.15
申请号 JP20080147345 申请日期 2008.06.04
申请人 XIGEN SA 发明人 BONNY CHRISTOPHE
分类号 C12Q1/70;G01N33/53;A61K31/7088;A61K38/00;A61K38/06;A61K45/00;A61K47/42;A61K47/48;A61K48/00;A61P3/10;A61P5/48;A61P9/00;A61P9/04;A61P11/00;A61P25/00;A61P25/28;A61P31/12;A61P35/00;C07K1/04;C07K5/10;C07K5/103;C07K5/107;C07K5/11;C07K5/113;C07K7/06;C07K7/08;C07K19/00;C12N15/09;G01N33/566 主分类号 C12Q1/70
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