| 摘要 |
The invention relates to highly concentrated DHA and EPA formulations in a soft gel capsule. A capsule may contain at least 80% omega-3 fatty acids, salts or derivatives thereof, where EPA and DHA are present in relative amou nts of greater than or equal to 3:1 or less than or equal to 1 :3, and const itute at least 75% to greater than 95% of the total fatty acids present in t he capsule. Capsules of the invention may be provided in a blister package s o as to provide clean and protected oils that are easy to travel with. Compl iance is improved with one-pill- a-day dosing and the days of the week impri nted on the foil packing. Anitoxidant protection may be provided by rosemary and vitamin C. The invention also provides a methods of treatment, modulati on or prophalaxis of coronary disease, altering serum LDL-cholesterol and/or HDL-cholesterol, lowering serum triglycerides, lowering blood pressure, pul se rate, altering the activity of the blood coagulation factor VII complex, mild hypertension, protection from cyclosporine toxicity in kidney transplan t, rheumatoid arthritis, development and progression of retinopathy, hypertr iglyceridemia, and neurological disorders in a subject. |
