Esmolol formulation

摘要

An aqueous, sterile pharmaceutical composition that is suitable for parenteral administration for the treatment of cardiac conditions is described. The composition has a pH of between 3.5 and 6.5 and comprises (a) 0.1-500 mg/ml of methyl-3-[4-(2-hydroxy-3-isopropylamino) propoxy] phenylpropionate hydrochloride (esmolol hydrochloride), (b) 0.01-2 M of a buffering agent, (c) 1-500 mg/ml of an osmotic-adjusting agent and (d) a pH-adjusting agent.