发明名称 |
8-beta-substituted estratrienes as selectively active estrogens |
摘要 |
The invention refers to 8²-substituted estra-1,3,5(10)-triene derivatives of general formula I
their use as pharmaceutical active ingredients, which have in vitro a higher affinity to estrogen receptor preparations from rat prostates than to estrogen receptor preparations from rat uteri and in vivo a preferential action in the ovary in comparison to the uterus, their production, their therapeutic use and pharmaceutical dispensing forms that contain the new compounds.
|
申请公布号 |
EP2014672(A1) |
申请公布日期 |
2009.01.14 |
申请号 |
EP20070075600 |
申请日期 |
2007.07.12 |
申请人 |
BAYER SCHERING PHARMA AKTIENGESELLSCHAFT |
发明人 |
PETERS, OLAF;BRAEUER, NICO;THIEME, INA;PRELLE, KATJA;MUHN, HANS-PETER |
分类号 |
C07J1/00;A61K31/565;A61P5/30 |
主分类号 |
C07J1/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|