MARKER GENES BASED ON THALIDOMIDE TREATMENT FOR SCREENING OF DRUG INDUCING TERATOGENICITY AND SCREENING METHOD USING THEREOF

摘要

A marker gene, a DNA microarray chip for screening the teratogenecity inducing drugs, and a method for screening the teratogenecity inducing drugs by using the chip are provided to the drugs inducing teratogenecity to be screened effectively. A marker gene is used to screen the teratogenecity inducing drugs and comprises the gene selected from Genebank NM_032199 [AT rich interactive domain 5B (MRF1-like)], Genebank BX647857 [Ankyrin repeat and SOCS box-containing 5], Genebank NM_013314 [B-cell linker], Genebank AB018258 [ATPase, Class V, type 10B], Genebank BX111592 [Transcribed locus], etc.