| 发明名称 |
BENZIMIDAZOLE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AS FXR AGONISTS AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME. |
| 摘要 |
<p>The invention is concerned with novel benzimidazole derivatives of formula (I) wherein R1 to R8 are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds bind to FXR and can be used as medicaments.</p> |
| 申请公布号 |
MX2008015923(A) |
申请公布日期 |
2009.01.13 |
| 申请号 |
MX20080015923 |
申请日期 |
2007.06.18 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG. |
发明人 |
ALEXANDER CHUCHOLOWSKI;BERND KUHN;HANS RICHTER;NARENDRA PANDAY;UWE GRETHER;KONRAD BLEICHER;HENRIETTA DEHMLOW;FRANZ SCHULER;RAINER E. MARTIN;GREGORY MARTIN BENSON;ERIC J. NIESOR;XAVIER MARIE WAROT;MATTHEW WRIGHT;MINMIN YANG |
| 分类号 |
C07D235/18;A61K31/4184;A61P3/00;A61P25/00;A61P35/00;C07D403/04;C07D403/10;C07D409/04;C07D409/10 |
主分类号 |
C07D235/18 |
| 代理机构 |
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