发明名称 |
Hybrid magnet devices for molecule manipulation and small scale high gradient-field applications |
摘要 |
The present disclosure provides a high performance hybrid magnetic structure made from a combination of permanent magnets and ferromagnetic pole materials which are assembled in a predetermined array. The hybrid magnetic structure provides means for separation and other biotechnology applications involving holding, manipulation, or separation of magnetizable molecular structures and targets. Also disclosed are hybrid magnetic tweezers able to exert approximately 1 nN of force to 4.5 mum magnetic bead. The maximum force was experimentally measured to be ~900 pN which is in good agreement with theoretical estimations and other measurements. In addition, a new analysis scheme that permits fast real-time position measurement in typical geometry of magnetic tweezers has been developed and described in detail.
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申请公布号 |
US7474184(B1) |
申请公布日期 |
2009.01.06 |
申请号 |
US20060355462 |
申请日期 |
2006.02.15 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
HUMPHRIES DAVID E.;HONG SEOK-CHEOL;COZZARELLI, LEGAL REPRESENTATIVE LINDA A.;POLLARD MARTIN J. |
分类号 |
H01F7/02;G01N33/553 |
主分类号 |
H01F7/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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