发明名称 N-OXIDES OF VENLAFAXINE AND O-DESMETHYLVENLAFAXINE AS PRODRUGS
摘要 Embodiments of the invention relate to a compound of formula (1), or a tautomer, stereoisomer, hydrate, or solvate thereof, wherein R1 is H or CH3. Other embodiments of the invention relate to a pharmaceutical composition containing these compound, to methods for preparing these compounds, and to methods for preparing compositions containing these compounds. Yet other embodiments of the invention relate to the uses of these compounds and compositions containing it, such as for the manufacture of medicaments and pharmaceutical compositions for treating a condition chosen from depression, major depressive disorder, generalized anxiety disorder, obsessive compulsive disorder, social anxiety disorder, panic disorder, general depressive disorders, diabetic neuropathy, migraine and hot flashes.
申请公布号 US2009005455(A1) 申请公布日期 2009.01.01
申请号 US20080143919 申请日期 2008.06.23
申请人 SOLVAY PHARMACEUTICALS, B.V. 发明人 TURSKI LECHOSLAW A.;STOIT AXEL;KRUSE CORNELIS G.;VADER SANDER;TULP MARTINUS TH.M.
分类号 A61K31/135;A61P25/00;C07C215/56;C07C217/74 主分类号 A61K31/135
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