Method of irradiation using process of adding vitamin C

摘要

Disclosed is an irradiation method which includes addition of vitamin C during sterilization of bone restorative demineralized bone matrix (DBM) with irradiation, so as to inhibit reduction of physical properties of a carrier containing DBM caused by irradiation and protect DBM formable bone morphogenetic protein (BMP) from irradiation. The method according to the present invention can provide bone restorative materials with more excellent stability and effectively controlled modification of physical properties by employing a sterilization process accompanied with addition of vitamin C during irradiation.