发明名称 QUINOXALINYL MACROCYCLIC HEPATITIS C VIRUS SERINE PROTEASE INHIBITORS
摘要 The present invention relates to compounds, including compounds of Formula I, or a pharmaceutically acceptable salt, ester, or prodrug, thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
申请公布号 US2009005387(A1) 申请公布日期 2009.01.01
申请号 US20080016599 申请日期 2008.01.18
申请人 NIU DEQIANG;LIU DONG;MOORE JOEL D;XU GUOYOU;SUN YING;GAI YONGHUA;TANG DATONG;OR YAT SUN;WANG ZHE 发明人 NIU DEQIANG;LIU DONG;MOORE JOEL D.;XU GUOYOU;SUN YING;GAI YONGHUA;TANG DATONG;OR YAT SUN;WANG ZHE
分类号 A61K31/495;A61K31/497;A61P31/00 主分类号 A61K31/495
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