发明名称 METHOD FOR DETECTION OR TREATMENT OF GRAFT VERSUS HOST DISEASE
摘要 Disclosed is a method for detecting a graft versus host disease, which is characterized by measuring the quantity of CCL8 protein in a sample collected from a subject and utilizing the measurement value as a measure of the diagnosis or course of the graft versus host disease. Also disclosed is a diagnostic agent for a graft versus host disease, which comprises an anti-CCL8 antibody. The method enables the diagnosis of the occurrence of a graft versus host disease or the monitoring of the course of a graft versus host disease, particularly the differential diagnosis between a graft versus host disease and an infectious disease. Further disclosed is a therapeutic method for a graft versus host disease by using an anti-CCL8 antibody.
申请公布号 WO2009001545(A1) 申请公布日期 2008.12.31
申请号 WO2008JP01625 申请日期 2008.06.23
申请人 SAPPORO MEDICAL UNIVERSITY;IMMUNO-BIOLOGICAL LABORATORIES CO., LTD.;HORI, TSUKASA;KOKAI, YASUO;NAISHIRO, YASUYOSHI;TSUTSUMI, HIROYUKI;IMAI, KOHZOH 发明人 HORI, TSUKASA;KOKAI, YASUO;NAISHIRO, YASUYOSHI;TSUTSUMI, HIROYUKI;IMAI, KOHZOH
分类号 G01N33/53;A61K39/395;A61P37/06;G01N27/62;G01N30/72;G01N30/88;G01N33/15;G01N33/50 主分类号 G01N33/53
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