METHOD FOR DETECTION OR TREATMENT OF GRAFT VERSUS HOST DISEASE
摘要
Disclosed is a method for detecting a graft versus host disease, which is characterized by measuring the quantity of CCL8 protein in a sample collected from a subject and utilizing the measurement value as a measure of the diagnosis or course of the graft versus host disease. Also disclosed is a diagnostic agent for a graft versus host disease, which comprises an anti-CCL8 antibody. The method enables the diagnosis of the occurrence of a graft versus host disease or the monitoring of the course of a graft versus host disease, particularly the differential diagnosis between a graft versus host disease and an infectious disease. Further disclosed is a therapeutic method for a graft versus host disease by using an anti-CCL8 antibody.
申请公布号
WO2009001545(A1)
申请公布日期
2008.12.31
申请号
WO2008JP01625
申请日期
2008.06.23
申请人
SAPPORO MEDICAL UNIVERSITY;IMMUNO-BIOLOGICAL LABORATORIES CO., LTD.;HORI, TSUKASA;KOKAI, YASUO;NAISHIRO, YASUYOSHI;TSUTSUMI, HIROYUKI;IMAI, KOHZOH
发明人
HORI, TSUKASA;KOKAI, YASUO;NAISHIRO, YASUYOSHI;TSUTSUMI, HIROYUKI;IMAI, KOHZOH