发明名称 |
Pyrazine derivatives useful as adenosine receptor antagonists |
摘要 |
The present invention provides a compound of formula (I) wherein: A represents an optionally substituted monocyclic or polycyclic aryl or heteroaryl group B represents an optionally substituted monocyclic nitrogen-containing heteroaryl group; and either a) R1 and R2 represent hydrogen or specified substituents, or b) R2, R1 and the —NH— group to which R1 is attached, form a moiety selected from the moiety of formulae (IIa) and (IIb): (IIa) These compounds are useful as antagonists of the A2B receptor, for instance in the treatment of asthma. |
申请公布号 |
ZA200800353(B) |
申请公布日期 |
2008.12.31 |
申请号 |
ZA20080000353 |
申请日期 |
2008.01.11 |
申请人 |
LABORATORIOS ALMIRALL, S.A. |
发明人 |
VIDAL JUAN, BERNAT;ESTEVE TRIAS, CHRISTINA;SOCA PUEYO, LIDIA;EASTWOOD, PAUL, ROBERT |
分类号 |
A61K;A61P;C07D |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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