CHEWABLE BILAYER TABLET FORMULATION

摘要

Disclosed herein a tablet formulation of an objectionable tasting drug cetirizine or its pharmaceutically acceptable salt in a form of chewable bilayer tablet, wherein said formulation comprising said cetirizine, a combination of water-insoluble and water- soluble polymer in ratio of about 1 :0.5 to about 1 : 5 and low molecular weight polyol, wherein the molar ratio of the said low molecular weight polyol to said cetirizine is more than 10, and inactive formulation layer comprising beta- cyclodextrin and other pharmaceutical acceptable excipients. Further, the present invention provides a process for preparation of said formulation.