The present invention relates to. modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof of formula (I), including Cystic Fibrosis Transmembrane Conductance Regulator ("CFTR"), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
申请公布号
WO2008127399(A3)
申请公布日期
2008.12.31
申请号
WO2007US83464
申请日期
2007.11.02
申请人
VERTEX PHARMACEUTICALS INCORPORATED;HADIDA RUAH, SARA;ZHOU, JINGLAN;MILLER, MARK;BEAR, BRIAN
发明人
HADIDA RUAH, SARA;ZHOU, JINGLAN;MILLER, MARK;BEAR, BRIAN