ALFUZOSIN FORMULATIONS, METHODS OF MAKING AND METHODS OF USE
摘要
Alfuzosin compositions comprising alfuzosin and a release-retarding matrix comprising about 40 to about 80 % (by weight) hydroxypropyl methyl cellulose with a maximum apparent viscosity of about 5600 cP, wherein the compositions are bioequivalent to the reference dosage form of NDA #021287 are disclosed. Alfuzosin compositions comprising alfuzosin and a release-retarding matrix comprising about 40 to about 80 % (by weight) hydroxypropyl methyl cellulose (HPMC) with a maximum apparent viscosity of about 5600 cP, wherein the dissolution profile of the compositions are substantially identical to the dissolution profile of the reference dosage form of NDA #021287 are also disclosed. Methods of making and using the alfuzosin compositions are also disclosed.
申请公布号
WO2008073388(A3)
申请公布日期
2008.12.31
申请号
WO2007US25260
申请日期
2007.12.10
申请人
MUTUAL PHARMACEUTICAL COMPANY, INC.;ARNOLD, KRISTIN;DU, JIE;NARINGREKAR, GANDHA, V.