LACTOSE-FREE, NON-HYGROSCOPIC AND ANHYDROUS PHARMACEUTICAL COMPOSITIONS OF DESCARBOETHOXYLORATADINE

摘要

STABLE PHARMACEUTICAL COMPOSITIONS OF DESCARBOETHOXYLORATADINE (DCL), A METABOLIC DERIVATIVE OF LORATADINE, FOR THE TREATMENT OF ALLERGIC RHINITIS AND OTHER HISTAMINE-INDUCED DISORDERS ARE DISCLOSED. THE COMPOSITIONS ARE FORMULATED TO AVOID THE INCOMPATIBILITY BETWEEN DCL AND REACTIVE EXCIPIENTS SUCH AS LACTOSE AND OTHER MONO-AND DI-SACCHARIDES. DISCLOSED COMPOSITIONS INCLUDE LACTOSE-FREE, NON-HYGROSCOPIC AND ANHYDROUS STABLE PHARMACEUTICAL COMPOSITIONS OF DCL.