COMPLEXES OF IL-15 AND IL-15RALPHA AND USES THEREOF

摘要

The present invention relates to agents that modulate interle?kin-15 ("IL-15") signal transduction or function ("Therapeutic Agents") and the use ol" those agents to modulate immune function. The Therapeutic Agents target the interaction between IL-15 and its receptor and modulate IL-15-induced signal transduction. The Therapeutic Agents may be formulated with polymers, such as poly-ß- 1- ?4-N-acetylglucosamine. for administration to a human subject to modulate IL-15-mediated immune function.