发明名称 GSK-3 INHIBITORS FOR THE TREATMENT OF OSTEOPOROSIS
摘要 The present invention relates to a new use of a compound of the formula (I) wherein R1 is NH2, piperazin-1-yl, 4-methylpiperazin-1-yl, 4-methyl-1,4-diazepan-1-yl or 4-ethylpiperazin-1-yl; R2 is hydrogen, fluoro, CH3, CH2CH3, OCH3, CF3 or OCF3; R3 is hydrogen, CH3 or fluoro; as a free base or a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for the prevention and/or treatment of bone-related disorders, osteoporosis and increasing bone formation, bone mineral density. The present invention further relates to a method of prevention and/or treatment of these disorders. ® KIPO & WIPO 2009
申请公布号 KR20080114717(A) 申请公布日期 2008.12.31
申请号 KR20087021787 申请日期 2008.09.05
申请人 ASTRAZENECA AB 发明人 BERG ANNA LENA;BHAT RATAN
分类号 C07D241/14;A61K31/497;A61P19/10;C07D403/08 主分类号 C07D241/14
代理机构 代理人
主权项
地址