A SHAPE-BASED APPROACH FOR SCAFFOLDLESS TISSUE ENGINEERING

摘要

Improved methods for tissue engineering are provided. More particularly, methods are provided for inducing differentiation of dermis-derived cells to serve as a source of chondrocytes and associated methods of use in forming tissue engineered constructs. One example of a method is a method for inducing differentiation of cells into chondrocytes comprising providing aggrecan sensitive isolated dermis cells and seeding the cells onto an aggrecan coated surface.