| 发明名称 |
6.5-PYRROLOPIPERIDINE TACHYKININ RECEPTOR ANTAGONISTS |
| 摘要 |
<p>The present invention is directed to certain hydroxymethyl ether hydroisoindoline compounds which are useful as neurokinin-1 (NK-1) receptor antagonists, and inhibitors of tachykinin and in particular substance P. The invention is also concerned with pharmaceutical formulations comprising these compounds as active ingredients and the use of the compounds and their formulations in the treatment of certain disorders, including emesis, urinary incontinence, LUTS, depression, and anxiety.</p> |
| 申请公布号 |
WO2009002770(A1) |
申请公布日期 |
2008.12.31 |
| 申请号 |
WO2008US67270 |
申请日期 |
2008.06.18 |
| 申请人 |
MERCK & CO., INC.;BAO, JIANMING;DEVITA, ROBERT, J.;LU, HUAGANG |
发明人 |
BAO, JIANMING;DEVITA, ROBERT, J.;LU, HUAGANG |
| 分类号 |
A61K31/40;A01N43/38;A61K31/405 |
主分类号 |
A61K31/40 |
| 代理机构 |
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