摘要 |
<p>The invention relates to the use of a pharmaceutically active derivative of N-phenylbenzamide of Formula (I) or of a pharmaceutically acceptable salt thereof, for preparing a medicament for the therapeutic treatment of Chronic Obstructive Pulmonary Disease (COPD). Compounds of Formula (I):
wherein R 1 is cyano, nitro, halogen, hydroxy, C 1 -C 4 alkyl, methoxy or tetrazol-5-yl group, R 2 is hydrogen, hydroxy or methoxy, R 3 is a tetrazol-5-yl group or hydrogen, R 4 and R 5 are hydrogen if R 3 is tetrazol-5-yl group, or R 4 and R 5 are independently selected from the group consisting of carboxy, methoxycarbonyl, ethoxycarbonyl and carbamoyl if R 3 is hydrogen, and R 6 is hydrogen or methyl.</p> |