发明名称 |
Nanoparticulate clopidogrel and aspirin combination formulations |
摘要 |
The present invention is directed to compositions comprising a nanoparticulate clopidogrel and aspirin combination, or salts or derivatives thereof, having improved clopidogrel bioavailability. The nanoparticulate clopidogrel particles, and optionally the nanoparticulate aspirin particles, of the composition have an effective average particle size of less than about 2000 nm and are useful in the prevention and treatment of pathologies induced by platelet aggregation. The clopidogrel and aspirin particles may also be formulated as a controlled release polymeric coating or matrix drug delivery system. |
申请公布号 |
ZA200800050(B) |
申请公布日期 |
2008.12.31 |
申请号 |
ZA20080000050 |
申请日期 |
2008.01.02 |
申请人 |
ELAN PHARMA INTERNATIONAL, LIMITED |
发明人 |
JENKINS, SCOTT;LIVERSIDGE, GARY G. |
分类号 |
A61K;A61P |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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