发明名称 TRI-SUBSTITUTED UREAS AS CYTOKINE INHIBITORS
摘要 <p>The present invention relates to 1,1,3-tri-substituted ureas which inhibit the extracellular release of inflammatory cytokines, said cytokines responsible for one or more human or higher mammalian disease states. The present invention further relates to compositions comprising said 1,1,3-tri-substituted ureas which inhibit the extracellular release of inflammatory cytokines, and methods for preventing, abating, or otherwise controlling enzymes which are understood to be the active components responsible for the herein described disease states.</p>
申请公布号 SI1747204(T1) 申请公布日期 2008.12.31
申请号 SI20050030424T 申请日期 2005.04.20
申请人 THE PROCTER & GAMBLE COMPANY 发明人 BRUGEL TODD ANDREW;TOWNES JENNIFER ANNE;CLARK MICHAEL PHILIP;SABAT MARK;GOLEBIOWSKI ADAM;DE BISWANATH;BERBERICH STEPHEN MATTHEW;BOSCH GREGORY KENT
分类号 A61K31/505;C07D239/48;C07D239/49;C07D401/12;C07D403/12;C07D405/12;C07D409/12 主分类号 A61K31/505
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