| 发明名称 |
Chiral 3-carbamoylmethyl-5-methyl hexanoic acids, key intermediates for the synthesis of (S)-Pregabalin |
| 摘要 |
The invention encompasses the synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid, (S)-Pregabalin, via the intermediate, (3R)-5-methyl-3-(2-oxo-2{[(1R)-1-phenylethyl]amino}ethyl)hexanoic acid.
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| 申请公布号 |
US7470812(B2) |
申请公布日期 |
2008.12.30 |
| 申请号 |
US20070894855 |
申请日期 |
2007.08.21 |
| 申请人 |
TEVA PHARMACEUTICAL INDUSTRIES LTD. |
发明人 |
KANSAL VINOD KUMAR;CHAURASIA BRIJNATH P.;TIWARI ANAND PRAKASH |
| 分类号 |
C07C205/00;C07D211/20;C07F7/04;C12P13/00 |
主分类号 |
C07C205/00 |
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