| 发明名称 |
PHARMACEUTICAL COMPOSITIONS COMPRISING A BASIC RESPECTIVELY ACIDIC DRUG COMPOUND, SURFACTANT AND A PHYSIOLOGICALLY TOLERABLE WATER-SOLUBLE ACID RESPECTIVELY BASE |
| 摘要 |
The invention provides a novel pharmaceutical composition comprising a basic respectively acidic drug compound, a surfactant and a physiologically tolerable water-soluble acid respectively base characterized in that the acid respectively base: drug compound ratio is at least 1:1 by weight. The composition provides improved drug release and uptake on administration into externally voiding body cavities or on topical administration. |
| 申请公布号 |
EA010971(B1) |
申请公布日期 |
2008.12.30 |
| 申请号 |
EA20050000891 |
申请日期 |
2003.11.25 |
| 申请人 |
JANSSEN PHARMACEUTICA N.V. |
发明人 |
VANDECRUYS ROGER, PETRUS, GEREBERN;PEETERS JOZEF;BREWSTER MARCUS, ELI |
| 分类号 |
A61K9/48;A61K9/00;A61K9/107;A61K9/14;A61K9/16;A61K9/20;A61K9/50;A61K31/505;A61K47/12;A61K47/38;A61K47/44 |
主分类号 |
A61K9/48 |
| 代理机构 |
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