发明名称 |
Optical determination of glucose utilizing boronic acid adducts |
摘要 |
The present invention concerns an improved optical method and optical sensing device for determining the levels of polyhydroxyl-substituted organic molecules in vitro and/or in vivo in aqueous media. The range of detection is between about 400 and 800 nm. In particular, a sensory devise is implemented in a mammal to determine sugar levels. Specifically, a dye is combined with a conjugated nitrogen-containing heterocyclic aromatic boronic acid-substituted bis-onium compound in the presence of a sugar, such as fructose or glucose. The viologens are preferred as the aromatic conjugated nitrogen-containing boronic acid substituted compounds. The method is useful to determine sugar levels in a human being.
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申请公布号 |
US7470420(B2) |
申请公布日期 |
2008.12.30 |
申请号 |
US20050296898 |
申请日期 |
2005.12.07 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
SINGARAM BAKTHAN;WESSLING RITCHIE A. |
分类号 |
A61B10/00;A61B5/00;A61B8/00 |
主分类号 |
A61B10/00 |
代理机构 |
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主权项 |
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地址 |
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