发明名称 |
Process for decreasing aggregate levels of pegylated protein |
摘要 |
The present invention is directed generally to recombinant methods for making a desired pegylated protein and pooling of same. The method(s) yield a polypeptide product containing reduced levels of aggregate thereof pooled to provide the desired pegylated isoforms thereof.
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申请公布号 |
US7470779(B2) |
申请公布日期 |
2008.12.30 |
申请号 |
US20030665361 |
申请日期 |
2003.09.22 |
申请人 |
PFIZER INC. |
发明人 |
BOYLE DENIS M.;BUCKLEY JOHN J.;JOHNSON GARY V.;STEINMEYER DAVID E.;TOAL MICHELE;AYKENT SERDAR;RATHORE ANURAG S. |
分类号 |
C07K14/00;C07K1/18;C07K14/52 |
主分类号 |
C07K14/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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